Expert Answers to Lab Test Questions

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    LaShanta Brice, DCLS, MLS(ASCP)CMSHCM

    LaShanta Brice, DCLS, MLS(ASCP)CMSHCM

    Doctor of Clinical Laboratory Science

    "Everywhere laboratory medicine is, there should be a laboratory professional."

    18+

    Years Experience

    Questions Answered

    Landon Stovall-Guthrie, DCLS, MLS(ASCP)

    Landon Stovall-Guthrie, DCLS, MLS(ASCP)

    Doctor of Clinical Laboratory Scientist

    "There is a lot behind the number on the lab report.”

    9+

    Years Experience

    Questions Answered

    Michele Palermo, MLS(ASCP), CLT(NYSED)

    Michele Palermo, MLS(ASCP), CLT(NYSED)

    Medical Laboratory Scientist

    "Enjoy The Little Things."

    3+

    Years Experience

    Questions Answered

    Margaret Alba, DOM, MLS(ASCP)CM, BB(ASCP)

    Margaret Alba, DOM, MLS(ASCP)CM, BB(ASCP)

    Medical Laboratory Scientist (MLS)

    "We get things spun, run, and done!"

    36+

    Years Experience

    Questions Answered

    Diagnostic Test Lookup

    Explore essential lab tests that support early detection, accurate diagnosis, and personalized treatment decisions. From routine screenings to specialized genetic analyses, this comprehensive resource covers diagnostic tests across major laboratory disciplines.

    Complete Blood Count (CBC)

    Measures red/white cells, hemoglobin, and platelets to assess overall blood health and detect various conditions like anemia or infection.

    Comprehensive Metabolic Panel

    Includes glucose, liver enzymes, kidney function markers, and electrolytes for comprehensive metabolic evaluation.

    Lipid Panel (Cholesterol)

    Measures total cholesterol, LDL, HDL, and triglycerides to assess cardiovascular risk and heart health.

    Thyroid Function Tests

    Evaluates TSH, Free T4, Free T3, and other thyroid hormones to assess thyroid gland function and metabolism.

    Hemoglobin A1c

    Reflects average blood glucose levels over 2-3 months, essential for diabetes screening and monitoring.

    Liver Function Tests (LFTs)

    Measures liver enzymes (ALT, AST, ALP, GGT) and bilirubin to assess liver health and detect hepatic conditions.

    Cancer Screening Markers

    Includes PSA, CA 15-3, AFP, and other tumor markers for early detection and monitoring of various cancers.

    Genetic & Molecular Testing

    BRCA1/2, Factor V Leiden, and other genetic tests for hereditary conditions and personalized medicine.

    Overview Lab Tests

    Complete Blood Count (CBC)

    Measures red/white cells, hemoglobin, and platelets to assess overall blood health and detect various conditions like anemia or infection.

    Comprehensive Metabolic Panel

    Includes glucose, liver enzymes, kidney function markers, and electrolytes for comprehensive metabolic evaluation.

    Lipid Panel (Cholesterol)

    Measures total cholesterol, LDL, HDL, and triglycerides to assess cardiovascular risk and heart health.

    Thyroid Function Tests

    Evaluates TSH, Free T4, Free T3, and other thyroid hormones to assess thyroid gland function and metabolism.

    Hemoglobin A1c

    Reflects average blood glucose levels over 2-3 months, essential for diabetes screening and monitoring.

    Liver Function Tests (LFTs)

    Measures liver enzymes (ALT, AST, ALP, GGT) and bilirubin to assess liver health and detect hepatic conditions.

    Cancer Screening Markers

    Includes PSA, CA 15-3, AFP, and other tumor markers for early detection and monitoring of various cancers.

    Genetic & Molecular Testing

    BRCA1/2, Factor V Leiden, and other genetic tests for hereditary conditions and personalized medicine.

    Clinical Chemistry Lab Tests

    Basic Metabolic Panel (BMP)

    Measures glucose, calcium, and electrolytes to assess kidney function and metabolism.

    Comprehensive Metabolic Panel (CMP)

    Includes BMP plus liver enzymes and proteins for full metabolic evaluation.

    Liver Function Tests (LFTs)

    Measures liver enzymes (ALT, AST, ALP, and GGT) and bilirubin to assess liver health.

    Glucose Test

    Screens for or monitors diabetes by measuring blood glucose levels.

    Lipid Panel (Cholesterol)

    Measures total cholesterol, LDL, HDL, and triglycerides for cardiovascular assessment.

    Kidney Function Tests

    Evaluates kidney function using blood creatinine, BUN, eGFR as well as urine tests.

    Electrolyte Panel

    Measures sodium, potassium, chloride, and bicarbonate for fluid and pH balance.

    Albumin Test

    Evaluates liver/kidney function via albumin level measurement.

    Hematology Lab Tests

    Complete Blood Count (CBC)

    Measures red/white cells, hemoglobin, and platelets for comprehensive blood assessment.

    Hemoglobin A1c

    Reflects average blood glucose over 2–3 months for diabetes monitoring.

    Reticulocyte Count

    Measures immature red blood cells to assess bone marrow activity.

    ESR (Sedimentation Rate)

    Detects inflammation by measuring how quickly red blood cells settle.

    Prothrombin Time (PT)/INR

    Monitors blood clotting function, especially important for warfarin therapy.

    Iron Studies

    Measures serum iron, ferritin, TIBC to assess iron deficiency or overload.

    Peripheral Blood Smear

    Microscopic examination of blood cells for detailed morphology analysis.

    Fibrinogen Test

    Assesses clotting protein levels important for bleeding disorders.

    Microbiology Lab Tests

    Urine Culture

    Identifies UTI-causing bacteria and determines antibiotic sensitivity.

    Blood Culture

    Detects bloodstream infections and identifies causative organisms.

    Throat Culture

    Detects strep throat and other bacterial throat infections.

    Sputum Culture

    Identifies lung infection pathogens for respiratory conditions.

    Stool Culture

    Detects harmful gut bacteria causing gastrointestinal infections.

    Wound Culture

    Identifies pathogens causing skin and soft tissue infections.

    COVID-19 PCR

    Detects SARS-CoV-2 genetic material for accurate COVID-19 diagnosis.

    Stool Ova and Parasite

    Screens for intestinal parasites and their eggs in stool samples.

    Infectious Disease Lab Tests

    Hepatitis Panel

    Tests for Hepatitis A, B, and C antibodies and antigens for liver infection screening.

    HIV Test

    Detects HIV antigen and antibodies for comprehensive HIV screening.

    Syphilis Testing

    Includes RPR and specific treponemal tests for syphilis detection.

    Group A Streptococcus

    Rapid detection of Group A strep infections for prompt treatment.

    Hepatitis B Surface Antigen

    Specific test for active Hepatitis B infection detection.

    Hepatitis C Antibody

    Screens for Hepatitis C exposure and chronic infection.

    RPR (Rapid Plasma Reagin)

    Latex-based screening test for syphilis detection.

    Infectious Disease Panel

    Comprehensive testing for multiple infectious agents simultaneously.

    Immunology Lab Tests

    Antinuclear Antibody (ANA)

    Screens for autoimmune diseases such as lupus and other connective tissue disorders.

    C-Reactive Protein (CRP)

    Indicates inflammation levels in the body for various conditions.

    Rheumatoid Factor (RF)

    Aids in diagnosing rheumatoid arthritis and related autoimmune conditions.

    Immunoglobulins (IgA, IgG, IgM)

    Tests immune system function and antibody production capabilities.

    Allergy Panel

    Identifies specific allergen sensitivities for environmental and food allergies.

    Procalcitonin

    Used to investigate bacterial sepsis and guide antibiotic therapy.

    Erythropoietin Test

    Measures hormone that stimulates red blood cell production.

    HLA Typing

    Tests tissue compatibility for organ transplantation procedures.

    Molecular/Genetic Lab Tests

    BRCA1/2 Mutation Test

    Screens for hereditary breast and ovarian cancer risk mutations.

    Factor V Leiden Test

    Screens for inherited blood clotting disorder increasing thrombosis risk.

    CFTR Mutation Test

    Confirms cystic fibrosis diagnosis through genetic mutation analysis.

    PCR (Polymerase Chain Reaction)

    Detects infectious DNA/RNA including HIV, COVID-19, and other pathogens.

    Next Generation Sequencing (NGS)

    Detects multiple genetic mutations simultaneously for comprehensive analysis.

    Whole Exome Sequencing

    Examines all protein-coding genes for rare genetic disorders.

    KRAS Mutation Test

    Guides cancer treatment decisions, especially for colorectal cancer.

    Chromosomal Microarray

    Identifies genetic changes linked to developmental disorders.

    Cancer Markers Lab Tests

    PSA (Prostate-Specific Antigen)

    Screens for and monitors prostate cancer in men.

    CA 15-3 / CA 27.29

    Used to monitor breast cancer treatment response and recurrence.

    AFP (Alpha-Fetoprotein)

    Liver cancer marker; also elevated in testicular and other germ cell tumors.

    Thyroglobulin

    Surveillance marker for patients treated for thyroid cancer.

    HE4 (Human Epididymis Protein 4)

    Ovarian cancer marker, often used with CA-125 for improved accuracy.

    Circulating Tumor DNA (ctDNA)

    Liquid biopsy detecting cancer mutations from blood samples.

    PD-L1 Expression Testing

    Determines eligibility for immune checkpoint inhibitor therapy.

    Chromogranin A

    Used in monitoring neuroendocrine tumors and treatment response.

    Autoimmune Lab Tests

    Anti-Mitochondrial Antibody (AMA)

    Primary biliary cholangitis.

    Anti-Scl-70 (Anti-Topoisomerase I)

    Associated with systemic sclerosis (scleroderma).

    Anti-Centromere Antibody

    Limited scleroderma (CREST syndrome).

    Anti-GBM (Glomerular Basement Membrane)

    Used to identify antibodies that would attack the filtering mechanism for the kidneys. Goodpasture's disease.

    Anti-MPO / Anti-PR3 (ANCA Panel)

    Used as an aid in patients suspected of inflammed blood vessels. Vasculitis (e.g., GPA, MPA).

    Anti-SSA (Ro) and Anti-SSB (La)

    Used as an aid in patients suspected of Sjögren's syndrome and neonatal lupus.

    Anti-Jo-1

    Used as an aid in patients suspected of Dermatomyositis/polymyositis.

    Anti-Histone Antibodies

    Used as an aid in patients suspected of Drug-induced lupus. Used as an aid in patients suspected of Antiphospholipid syndrome.

    Cryoglobulins

    Seen in cryoglobulinemic vasculitis, sometimes linked to cancer or autoimmune disease.

    Serum Amyloid A (SAA)

    Inflammatory marker elevated in chronic autoimmune diseases and some cancers.

    Mixing Study

    A study used to work up coagulation issues expected due to Lupus.

    Cardiac Lab Tests

    Troponin

    Gold standard test for detecting heart muscle damage and myocardial infarction.

    NT-proBNP/BNP

    Heart failure biomarker for screening and monitoring cardiac function.

    CK-MB

    Cardiac-specific enzyme elevated after heart muscle damage.

    Lipid Panel

    Comprehensive cholesterol testing for cardiovascular risk assessment.

    C-Reactive Protein (hsCRP)

    High-sensitivity test for cardiovascular inflammation risk.

    Homocysteine

    Amino acid level associated with cardiovascular disease risk.

    D-Dimer

    Blood clot breakdown product useful in cardiac emergency evaluation.

    Cardiac Panel

    Comprehensive testing combining multiple cardiac biomarkers.

    Endocrinology Lab Tests

    Thyroid Function

    Thyroid function is evaluated using one or more of the following hormone levels: TSH, Free T4, Free T3, Total T4, Total T3, thyroglobulin, and anti TPO.

    Pregnancy Testing

    The following hormones are evaluated when suspecting a person is pregnant or working towards conception: hCG, FSH, LH, estradiol, prolactin.

    Testosterone

    Aids in the evaluation of patients suspected of hypogonadism, impotence.

    Sperm Test

    Used as an aid in evaluating male fertility as well as vasectomy success.

    Drug Testing Lab Tests

    Urine Drug Screen

    Comprehensive screening for drugs of abuse and therapeutic monitoring.

    THC (Marijuana)

    Detection of cannabis use for employment or legal purposes.

    Opiates Panel

    Tests for morphine, codeine, and other opiate compounds.

    Amphetamines

    Screens for amphetamine and methamphetamine use.

    Cocaine Metabolites

    Detects cocaine use through metabolite analysis.

    Benzodiazepines

    Screens for prescription and illicit benzodiazepine use.

    Pain Management Panel

    Monitors compliance and identifies undisclosed substances.

    Synthetic Drug Screen

    Advanced testing for synthetic cannabinoids and stimulants.

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